Development of TCRB CDR3 length repertoire of human T lymphocytes
نویسندگان
چکیده
منابع مشابه
Development of TCRB CDR3 length repertoire of human T lymphocytes.
The third complementarity-determining region (CDR3) of TCR interacts directly with antigenic peptides bound to grooves of MHC molecules. Thus, it is the most critical TCR structure in launching acquired immunity and in determining fates of developing thymocytes. Since length is one of the components defining the CDR3 heterogeneity, the CDR3 length repertoires have been studied in various T cell...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2004
ISSN: 1460-2377
DOI: 10.1093/intimm/dxh046